Přehled

The targeted research group HBV Cure at the Institute of Organic Chemistry and Biochemistry Prague (IOCB Prague) led by Gabriel Birkuš, is focused on the discovery of novel therapies to treat chronic hepatitis B and other viral infections, cancer, and inflammatory disorders.

We are seeking a highly motivated technician to join our multidisciplinary team to participate in the collection and processing of samples from mouse models, work with tissue cultures, molecular biology, immunology, and biochemistry experiments, work in a BSL3 laboratory, and other activities related to projects focusing on the development of HBV and cGAS inhibitors.

We offer you the opportunity to master laboratory work in a top international team and participate in the development of compounds for the future treatment of serious diseases.

Work description:

  • Analysis of immune response (qPCR, Luminex)
  • Immunochemical testing (ELISA, Immunoprecipitations)
  • Work with cell cultures
  • DNA and RNA isolation from tissues and tissue culture samples, isolation of plasmid DNA
  • Work in BSL2 and BSL3 laboratories
  • Work with in vivo mouse models (collection and processing of samples)
  • Data processing and presentation (Microsoft Office)

We require:

  • University degree (Bc. or M.S. degree) within a field of virology, immunology, molecular biology, biochemistry, bioanalytics or pharmacy
  • Previous laboratory experience in a biochemistry/molecular biology laboratory is an advantage
  • Willingness to work with mouse models is an advantage
  • Knowledge of standard molecular biology/biochemistry techniques
  • Independence, accountability, and reliability
  • Basic computer skills (Microsoft Office)
  • Good communication skills in English

We offer:

  • Work in a well-established, internationally recognised scientific institution
  • Working in a progressive multidisciplinary scientific team of medicinal chemists, virologists, immunologists, computational chemists, and biochemists
  • Training and opportunities for further education through specialized courses
  • 5 weeks of vacation + 4 personal leave days
  • Financial support for parents with children up to 4 years old, coming back from parental leave

Additional information:

  • Fixed-term employment contract for 1 year with the possibility of extension
  • Full-time employment
  • Start date possible immediately or by agreement
  • Workplace located in Prague 6 – Dejvice, within walking distance from the Dejvická metro station

How to apply:

Your short cover letter with a structured CV with contact information of two references should be sent to zuzana.horejsi@uochb.cas.cz by 30 September 2025.

Source: https://www.uochb.cz/en/open-positions/371/technician-position

IOCB Prague (Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences) is a leading, internationally recognized scientific institution whose main mission is basic research in the fields of chemical biology and medicinal chemistry, organic and materials chemistry, natural products chemistry, biochemistry and molecular biology, physical chemistry, theoretical chemistry, and analytical chemistry. An integral part of IOCB’s mission is the transfer of basic research results into practical applications. The strong emphasis on interdisciplinary research leads to a number of applications in medicine.

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