Overview

Photoluminescent nanodiamonds represent a novel type of quantum biosensor that exploits changes in luminescent properties in response to external stimuli. Compared to classical sensors, they offer the benefits of high sensitivity and resolution but are often nonspecific. The aim of the project is to chemically functionalize these sensors for specific and sensitive detection in biologically relevant environments. To achieve this, the student will employ covalent surface modifications of nanosensors in a colloidal state and subsequently characterize them. The functionality of the constructed nanosensors will be verified using a quantum confocal microscope with advanced pulse sequences. The outcome of the project will be time-resolved, localized quantum detection of specific molecules. The expected knowledge of the applicant should be at the level of a completed Master’s degree in the field of biophysics, chemical physics or physical chemistry. The work will be carried out by the Synthetic Nanochemistry team at the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences.

University:

Faculty of Chemical Engineering, UCT Prague; Faculty of Mathematics and Physics & Faculty of Science, Charles University

Group:

Petr Cígler Group, Synthetic Nanochemistry

Tutor:

Mgr. Petr Cígler, Ph.D.

Field of study:

Chemical physics and sensoric, Physical Chemistry