Overview

The Czech Centre for Phenogenomics (CCP) is a leading research infrastructure providing specialized services for the biomedical and biotechnology community, focusing on genome editing, animal model research, and phenotyping.

To strengthen our team working on preclinical R&D projects related to skin diseases, we are seeking a motivated postdoctoral scientist or junior researcher who will be focused on the characterisation of Prader-Willi syndrome (PWS) mouse and cellular models and test preclinical therapeutic approaches for neurodevelopmental disorder, especially PWS, alongside other team members.

Work description and responsibilities:

  • Preclinical research of PWS in connection with a patient foundation
  • Molecular biology and cell culture (iPSC) work
  • Mouse model phenotyping analysis incl. behavioral and metabolism tests
  • Development of therapeutic AAV vectors, delivery studies, efficacy studies
  • Working towards agreed deadlines, identifying and troubleshooting risks at each step

Required skills/qualification:

  • PhD or equivalent in a biological subject or related field
  • Experience in a relevant position, particularly in molecular biology epigenetics, neurobiology, metabolism and mammalian cell culture
  • Experience with mouse models (breeding, genotyping, colony maintenance)
  • Experience with in vivo phenotype analysis, metabolic testing is of advantage
  • Ability to work independently, lead and supervise students
  • Proficiency in English

CCP, the top Czech science center, is in a modern research building offering superb research facilities, international and enthusiastic working environment with opportunities to bring own ideas into practice and create own research projects.

What We Offer:

  • An extendable contract with a competitive salary scale based on performance
  • Full-time position; the selected candidate will be offered a one-year contract as a starting arrangement with potential for long-term extension based on demonstrated ability
  • Flexible working hours
  • Flexible start date
  • There are possibilities for professional growth and further education
  • Workplace: CCP building at BIOCEV campus, Vestec (near Prague)

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