Overview
Organic chemistry deals with isolation, synthesis, determination of the structure of organic compounds and the study of the relationships between the structure and properties of organic substances using chemical and physical methods.
Start of studies in the winter semester (October)
Opening of applications and publication of the dissertation topics: 15. 2. 2026
Application by: 30. 4. 2026
Detailed information about the study programme
Offer of dissertation topics:
- Application of organocatalysis in the synthesis of inherently chiral molecules
- AzaHeteroarylBora[2.2]Paracyclophanes as CPL Emitters (AHBE)
- Catalysis with anions as nucleophiles
- Catalytic stereoselective synthesis of atropisomers and other bioactive molecules
- Catalytic stereoselective synthesis of cyclic atropisomers
- Construction of N-trifluoromethylated compounds as new building blocks in life science from azidofluoroalkanes
- Design and Investigation of Enantioselective Reactions Mediated by N-Heterocyclic Carbenes
- Design and Synthesis of Metalloenzyme Inhibitors Targeting Human Pathogens
- Design and synthesis of modified RNA and XNA as potential therapeutics
- Design and synthesis of MTAN inhibitors
- Development of innovative synthetic methods using transition-metal catalysis
- Display of sugars and glycans on DNA
- Enzymatic synthesis of modified oligonucleotides on solid support
- Glycine alkoxyamines for New Bioconjugation Methodologies
- NMR Studies of Solvation and Crystal Packing Effects in Molecular Systems
- PCP-based Ligands and Catalysts: Synthesis and Catalytic Activity
- P-Chiral Phosphines as Asymmetric Organocatalysts
- PRMT5/MAT2 inhibitors with potential anticancer properties
- Selection and optimization of modified DNA and XNA aptamers
- Spin Interactions and Multiplicity as a Tool for Reactivity Control
- Stable Nitrogen-Heterocyclic Radicals for the Synthesis of Calcium Ion Channel Inhibitors
- Study of the formation of “superchiral” molecular π-conjugated architectures through chemical synthesis and/or controlled self-assembly, with a focus on their structural and chiral properties.
- Synthesis and application of 13C-labelled radical, nucleophilic and electrophilic trifluoromethylating reagents
- Synthesis and investigation of azadienes for use in bioorthogonal reactions
- Synthesis and Modification of Polycyclic Aromatics (SYMPA)
- Synthesis of antifungal compounds and tool for diagnosis of fungal infections
- Synthesis of targeted kinase degraders as experimental therapeutics
- Tailored chelators for selective recovery of critical metals
- The topic of the thesis is the synthesis of new helical ligands/catalysts derived from helicenes and their application in enantioselective catalysis
- Utilization of non-fossil carbon sources for the preparation of organic molecules
Profile of the graduate
The graduate has a general overview in chemistry fields and a detailed overview of aspects of organic chemistry usable in practice both in chemistry research and experimental work as well as in the management of projects or a chemical laboratory. He is able to propose research projects, plan a solution strategy, lead the team, formulate reports, and prepare the manuscripts of publications. A broad overview gained in the multi-thematic environment of the university allows for a considerable degree of adaptability both with regard to the topics being processed and the work position.
Application submission
The application is submitted electronically through the Charles University study information system. The completed application must be submitted electronically in the study information system no later than on 30. 4. 2026 for study programmes starting in the winter semester (October) and no later than on 15. 12. 2025 for study programmes starting in the summer semester (April).
The admission fee is 100 EUR and it is paid for each submitted application.
Required application appendice is the agreement of a supervisor in the format of the following form available here. We recommend reaching out to the supervisor as soon as possible (ideally before 31. 3. 2026 for study programmes starting in the winter semester and before 30. 11. 2025 for study programmes starting in the summer semester), so the application could be send out in time in case the agreement is granted.
Entrance exam
The regular date of entrance exam for all doctoral programmes starting in the winter semester (October) is in June 2026 (to be specified), an alternative date is in June 2026 (to be specified).
The regular date of entrance exam for all doctoral programmes starting in the summer semester (April) is 4. – 5. 2. 2026, an alternative date is 11. – 12. 2. 2026.
The request for an alternative day is submitted and approved via the electronic information system.
The form of the entrance exam is an oral interview, which mainly concerns the issues of the planned dissertation and the candidate’s knowledge within the field of expertise of the given study programme.
Find more information in:
- Conditions of the admission procedure for doctoral study programmes at the Faculty of Science, Charles University, for study programmes starting in the winter semester (October)
or - Conditions of the admission procedure for doctoral study programmes at the Faculty of Science, Charles University, for study programmes starting in the summer semester (April).
Important links
Applicants with specific needs
If you have a physical handicap, you can apply for a modification of the entrance exam. For more information read the Conditions of the admission procedure for doctoral study programmes.
Departments involved in this programme
Department of Organic Chemistry
Guarantor of the study programme
doc. RNDr. Jindřich Jindřich, CSc.
jindrich.jindrich@natur.cuni.cz
Do you have a question?
Complete information about the admission procedure can be found on the website for applicants. For questions, please contact the admissions contact persons.
