Přehled
Are you a recent PhD graduate in molecular and cell biology, biochemistry, or biophysics looking for an exciting postdoctoral opportunity? Join our team for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate.
We are seeking a highly motivated and enthusiastic candidate with a PhD in the relevant fields. Prior postdoctoral experience is not required; we welcome candidates who are eager to learn and have a strong passion for research. Good communication skills and the ability to collaborate with multiple teams are also important.
As a postdoctoral researcher on our team, you will have the opportunity to use advanced proteomics and unique chemical probes to study the Haspin interactome and its function in different stages of the cell cycle. You will also investigate the role of Haspin in plasticity regulation and cell fate decision making, and evaluate its potential as a therapeutic target.
If you are interested in this opportunity, please send your CV, cover letter, and contact information for at least three referees to Karel Souček at ksoucek@ibp.cz. We welcome all applicants who are interested in joining our team and embarking on an exciting research journey with us.
RECENT PUBLICATIONS:
- Kvokackova, B., et al. Single-cell protein profiling defines cell populations associated with triple-negative breast cancer aggressiveness. Mol Oncol, 2022.
- Muresan XM, et al: Toll-like receptor 3 (TLR3) overexpression induces invasion of prostate cancer cells, whereas its activation triggers apoptosis. Am J Pathol 2022.
- Drapela S, et al.: High-Throughput, Parallel Flow Cytometry Screening of Hundreds of Cell Surface Antigens Using Fluorescent Barcoding. Apoptosis and Cancer: Methods and Protocol. Edited by Barcenilla H, Diaz D. New York, USA: Springer Nature, 2022.
- Remsik J, et al.: TGF-beta regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells. Sci Rep 2020, 10:11396.
- Drapela S, et al.: The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe. Mol Oncol 2020, 14:2487-503.
