Přehled

Ref. No. UKFaF/483132/2025

Charles University, Faculty of Pharmacy in Hradec Králové, represented by the Dean of the Faculty, announces an open competition according to the Act No. 111/1998 Coll., on Higher Education Institutions

to fill research position:

Researcher – PhD Student

Place of work: Hradec Králové, Czech Republic

We are seeking a highly motivated and talented PhD candidate to join our research group focused on novel synthetic methodologies and medicinal chemistry for drug discovery. This PhD project will specifically involve the synthesis of novel benzoquinone ansamycin derivatives for use in key medicinal chemistry applications such as cancer and neurodegenerative conditions.

The successful candidate will gain hands-on experience in advanced synthetic ad purification techniques, modern analytical methods (NMR, MS, IR, HPLC), and problem-solving in a dynamic and collaborative research environment. As part of our international collaborations, travel for conferences and research exchange visits is anticipated within the project.

Responsibilities:

  • Design and execute single/multi-step organic syntheses.
  • Characterise synthesised compounds using a range of analytical techniques.
  • Analyse and interpret experimental data.
  • Maintain accurate laboratory records and present research findings.
  • Contribute to scientific publications and conference presentations.
  • Actively participate in group meetings and departmental seminars.
  • Assist in the supervision and training of junior students.
  • Assist in the delivery of lab practicals, and develop teaching experience.
  • Immediate escalation of any identified risks to a superior position.

Essential Criteria:

  • Education: A Master’s degree (Mgr. or Ing. equivalent) or an excellent Bachelor’s degree (with strong research experience) in Organic Chemistry, Medicinal Chemistry, Chemical Sciences, or a closely related field.
  • Academic Excellence: A strong academic record demonstrating proficiency in organic chemistry principles.
  • Practical Experience: Demonstrated hands-on experience in a synthetic organic chemistry laboratory, including proficiency with standard reaction setups, purification techniques (column chromatography, recrystallisation), and basic analytical methods.
  • Language Skills: Excellent command of English (both written and oral) for scientific communication.
  • Motivation & Independence: High level of motivation, ability to work independently, and a strong problem-solving aptitude.
  • Teamwork: Ability to work effectively as part of a research team.Excellent organisational and communication skills.High level of work commitment.
  • Strong willingness to learn new things continuously.

Desirable Criteria:

  • Experience with air-sensitive chemistry, metal-catalysed reactions and organometallics.Familiarity with advanced analytical techniques (e.g., advanced NMR experiments, X-ray crystallography, mass spectrometry interpretation).
  • Demonstrated experience in scientific writing (e.g., Bachelor’s/Master’s thesis, project reports, contributions to publications).
  • Experience with literature searching databases (e.g., SciFinder, Reaxys).Basic knowledge of medicinal chemistry.
  • Prior experience presenting research findings at seminars or conferences.
  • Prior experience with supervising chemistry experiments.Prior experience of teaching.

Application must include the following:

  • First and last name of the applicant
  • Date and place of birth
  • Nationality
  • Place of residence/current address
  • Date and signature
  • Contact information (email address, phone number)

Candidates are expected to submit following information with the application:

  • CV including writing experience, any publications, professional skills and past research experience detailing the institution and research supervisor(s).
  • Professional cover letter outlining your motivation for applying.
  • Certified copy of the highest level of education completed.
  • Contact information for at least two academic referees who can provide letters of recommendation.
  • Other documents certifying required/desired knowledge and expertise.
  • Information duty and consent to the processing of personal data according to Regulation (EU) 2016/679 (General Data Protection Regulation) and Act No. 110/2019 Coll., on personal data processing, as amended

The application form and agreement including an acknowledgement about providing personal data are available for download below on this page http://www.faf.cuni.cz.

The estimated monthly wage: 26 000 CZK, possibility of increasing in case of successful grant capture

The start of work: 1 October 2025 or by agreement (no later than January 2026)

Type of employment contract: for 1 year, with the expectation that the contract will be extended.

Employment type:  by agreement

We offer:

  • Work for a prestigious educational and scientific institution of Charles University
  • Interesting work in cutting-edge research in the field of new technologies for translational research in pharmaceutical sciences
  • Access to state-of-the-art laboratory facilities and instrumentation.
  • Opportunity to participate in cutting-edge research and be part of an international interdisciplinary team in a vibrant and supportive research environment.
  • Possibility of cooperation with foreign experts from all over the world
  • Specialized professional growth and continuous education in a field with the perspective of long-term employment
  • Foreign scientific internships and participation in international conferences

We also offer:

  • working hours by agreement
  • 5 weeks of vacation per year + 5 personal development days
  • Discounted calls for employees and their family members
  • Meal allowance and other contributions from the social fund
  • possibility of using the services of the FAFÍK Children’s Group (a children’s group established at the Faculty of Pharmacy of the Charles University in Hradec Králové)
  • Discounted banking services (a package of above-standard benefits for all employees)
  • UK benefits (discounts and benefits for UK employees at external entities)

Detailed information on the benefits offered can be found on the faculty’s website www.faf.cuni.cz.

We kindly ask you to send the application form with all required documents and attachments by post or email no later than by 31. 8. 2025, 14:00 to the following address:

Charles University, Faculty of Pharmacy in Hradec Králové

Lenka Hulajová, DiS. – Personnel Department

Akademika Heyrovského 1203/8

500 03 Hradec Králové

Czech Republic

Email: hr@faf.cuni.cz

Please, clearly mark the envelope „Job Announcement – Researcher – PhD Student (KOBCH)“

We kindly ask you to send your application with all the required documents and attachments because without them your application is not complete, and you cannot be included in the list of candidates.

The announcer reserves the right to cancel the job announcement at any time during the course.

Contact person to provide further information on the content of the work:

Associate Prof./Docent. Dr. Russell Kitson, Ph.D. – Department of Organic and Bioorganic Chemistry

Phone: +420 495 067 217

e-mail: kitsonr@faf.cuni.cz

 

 

 

 

 

 

 

 

 

 

 

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