Přehled
In accordance with the The Competitive Hiring Process Code of Charles University, the Dean of the Faculty of Science of Charles University announces a competitive hiring process with a deadline for applications November 29, 2025
We invite applications for a Postdoctoral Researcher to join an ERC-funded project UNalphabeting the Central Dogma of Life, LIFE-19 (ERC-2024-COG, 101170416) at the Faculty of Science, Charles University (Prague, Czech Republic). The successful candidate will contribute to a highly interdisciplinary research effort aimed at re-designing a minimal bacterial cell towards a proteome based on 19 amino acids, addressing some of the most fundamental questions about the origin and evolution of the Central Dogma of Biology. This project explores how the genetic code and proteome composition can be systematically re-engineered to probe the boundaries of life’s biochemical systems. The work combines genome engineering, synthetic biology, protein design, and systems-level bioinformatics, with the goal of understanding and reshaping the molecular foundations of life as we know it. Responsibilities: Conduct experimental research in genome engineering, synthetic biology, and protein biochemistry. Design and implement high-throughput assays and automated workflows for cellular and molecular analyses. Perform bioinformatic and systems-level analyses of engineered strains and proteomes (optional) Collaborate within a larger interdisciplinary team of molecular biologists, chemists, and computational scientists. Mentor junior researchers and students involved in the project. We offer: A stimulating and collaborative research environment within the Faculty of Science, Charles University. Access to state-of-the-art molecular biology, bioinformatics, and automation facilities. Competitive salary and benefits according to Czech and EU academic standards. Opportunity to develop an independent research profile within a prestigious ERC-funded project. Living and working in downtown Prague, one of Europe’s most vibrant scientific and cultural cities. We require: Contact information for 3 references (Attachement Nr. 1)
Application Instructions
Application, which you can download here https://natur.cuni.cz/en/faculty/official-board/selection-procedures, with cover letter, curriculum vitae, list of publications, diplomas, research and teaching statement, must be send within 30 days from the announcement of the tender to the e-mail address: volnamista@natur.cuni.cz with subject “Výběrové řízení.”
If a candidate applies for more than one position, you must submit a separate application form for each selected position.
In justified cases, e.g., if the applicant completes his doctoral studies in the period between the submission of the application and the date of starting the employment relationship, the applicant must provide proof of the completed doctoral studies before signing the employment contract.
Candidates who progress to the second round of the selection procedure will be invited for an interview. The interview may be conducted by means of information and communication technology if justified, at the request of the candidate. The Committee may invite selected candidates to give a lecture to the academic community of the Faculty.
By sending your application, you agree that Charles University, Faculty of Science will process your personal data for the purpose of keeping records of job seekers in accordance with applicable laws.
Qualifications
Completed PhD in biochemistry, molecular biology, synthetic biology, or a related field. Demonstrated experience in one or more of the following: Genome engineering (e.g. CRISPR/Cas systems, recombineering) High-throughput screening and automation Protein design, enzymology, or catalysis Bioinformatics and data analysis Strong interest in fundamental biological questions and interdisciplinary collaboration. Excellent communication skills and ability to work both independently and as part of a team.
Required Documents
- structured CV
- education credentials, proof of academic degrees and ranks
- motivation letter
- Attachment no. 1 according to vacancy description
Job offer code: 202511-PD-PřF-1510-111
Published: 2025-10-30
Starting date by agreement: Yes
Hours per week: 40
Contract for an indefinite period: No
Expected end of contract: 2030-06-30
Work location: Prague