Institution Profile

The International Clinical Research Center (ICRC) of St. Anne’s University Hospital in Brno, Czech Republic is a new-generation research center focusing on the pathogenesis of diseases including finding new methods, technologies and medicaments for effective prevention, early diagnostics and individualized treatment. As a top Central European research center with more than 300 researchers, new technologies and EU grant support, we focus on research and development mainly in different fields of translational research.

FNUSA-ICRC is the holder of the „HR Excellence in Research Award“ given by the European Commission to a research institute. This award is a mark of quality and a lasting commitment to developing and creating favourable conditions for employees in the institution in accordance with the European Charter for Researchers and the Code of Conduct for the recruitment of researchers.

Team profile of Cellular and Molecular Immunoregulation group:

Dynamic research group focused on different aspects of the human immune response and on how the underlying mechanisms of immunity are linked with the development of disorders and pathologies. The main objectives are addressing i) the role of the immune response in the progression of sepsis and septic shock, including the study of long-term consequences; (ii) 3D models of human mucosal tissues enabling the study of the immune response in the microenvironment; (iii) immune cell signaling, in particular the role of the calcineurin-NFAT pathway in the development of susceptibility to infections; (iv) immunometabolism as a controlling mechanism of the immune response. Our thigh collaboration with clinicians creates the opportunity to perform basic research with a strong translational approach from the bench to the bedside approach.

WEB: https://www.fnusa-icrc.org/en/research/research-teams/pre-clinical-research/cellular-and-molecular-immunoregulation/


Join our team and take the next step in your career with us!

Starting date: negotiable

Workload: 1,0

We are looking for: a motivated candidate keen to develop translational research of immunology of acute and chronic inflammation. Candidate will work within a Horizon Europe funded project (BEATsep) dissecting impact of the immune system to development of long-term sepsis consequences. The candidate will work with clinical samples and use large spectra of methodology.

Your main tasks will include:

  • Blood sample preparation, tissue culture
  • Immunophenotyping of immune cells
  • Flow cytometry, ELISA and other imunology methods
  • Various functional assays (phagocytosis, oxidative burst, etc.)

Job criteria:

  • Ph.D. or equivalent received no longer than 7 years ago preferably in the field of immunology or cellular and molecular biology
  • Strong publication record declaring scientific productivity
  • Independent motivated researcher with ability to collaborate in team, and mentoring students
  • Excellent communication and writing skills in English
  • Strong background in immunological techniques, cellular and molecular assays
  • Experience with flow cytometry, gene expression and protein detection methods
  • Experience with bioinformatics is advantage

We offer:

  • Working in international multidisciplinary team of experts
  • Engagement in ambitious research projects
  • Vibrant, inspiring and highly collaborative environment
  • Well-equipped laboratories, good publication prospects
  • Personal growth, opportunities for further education and training
  • Competitive salary and fix-term contract for 1 year with possibility of extension
  • 25 days of holidays, 3 sickdays
  • Cafeteria benefit system – for example, a holiday allowance, allowance for cultural or sports activities and more
  • Discounts in our pharmacies, a contribution to the purchase of vitamin supplements
  • Accommodation for employees who are not from Brno

If you are interested, we will be glad to hear from you!

Send us your CV, a brief cover letter, copy of PhD diploma or official letter certifying submission of a doctoral thesis and two contacts for reference (all in English) to jan.fric@fnusa.cz and karolina.macharackova@fnusa.cz

We are pleased to consider all qualified applicants for employment without regard to age, gender, marital status, sexual orientation, race, color, religion, ethnicity, disability, national origin, nationality, political opinion or any other aspect unrelated to work.

By responding to this invitation and/or sending your CV and any other personal materials to St. Anne’s University Hospital, you consent to the collection, processing and storage of your personal data in accordance with Act No. 110/2019 Coll., the protection of personal data. You are providing St. Anne’s University Hospital with these data solely for the purpose of mediating employment, the period however being no longer than one year from submitting. Should you not reclaim the materials submitted by you, they will be discarded after the period has expired.