We are seeking a talented and motivated candidate to join our team to pursue the mechanisms and functions of primary cilia. The primary cilium is an antenna-like organelle that has emerged as a fundamental regulator of embryonic development as well as tissue homeostasis. Consequently, the deregulation of its assembly, maintenance, or function leads to numerous human diseases, collectively termed ciliopathies. It has been estimated that cilia dysfunctions are responsible for as many as 100 human diseases. However, the mechanistic explanation of primary cilia assembly and function, crucial for the understanding of cilia-related defects and their therapeutic targeting, is insufficient.
The successful candidate will join the lab of Dr. Lukáš Čajánek at Masaryk University in Brno. The lab has a long-term interest in the role of a kinase termed TTBK2, which has emerged as a master regulator of primary cilia across vertebrates.
The selected applicant will have access to unique research tools, state-of-the-art methodology, and advanced instrumentation (cellular and animal models, proteomics, gene editing, lentiviral transduction, live cell imaging, super-resolution microscopy, etc.).
For more information on the research themes in the lab, please visit: www.cajaneklab.com
The successful candidate should:
- be a researcher who has received a PhD or its equivalent within the last 7 years
- be a researcher who has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic in the field of research with a working time of at least 0.5 full-time equivalent, or who has been PhD student (or equivalent) abroad
- have a publishing record – in the last 3 years at least 3 publication outputs (“articles”) above the field median (at least 2 of them in Q1) listed by the Web of Science
- have a PhD in cell biology, molecular biology, or similar fields
- have a solid publication record in well-recognized scientific journals, including at least one first-author research article
- be skilled in mammalian cell culture, a broad range of molecular biology techniques, and advanced microscopy (considered as an advantage)
- prove the interest and ability to tackle scientific challenges
- be capable of independent planning of experiments to explore hypotheses, prioritizing tasks, and solving project-related issues
- have excellent communication and documentation skills
- be highly motivated, creative, and self-driven
- to become a part of an enthusiastic and curiosity-driven scientific team with international collaborations and sufficient grant support
- a challenge to address fundamental biological questions
- full support of the administrative and project offices
- support of the Welcome office for the successful applicant and his/her family
- full-time contract for 2 years (with the possibility of extension)
Anticipated start date: The position is available from June 2023 or upon agreement, with an initial appointment for 2 years.
The submission deadline is 28th February 2023.
Please submit e-application at the website: https://www.muni.cz/o-univerzite/kariera-na-mu/volna-mista/75667.
The application should include:
- a CV including a list of publications and contact (email) for 2 references
- a diploma (recognition for diplomas from foreign institutions)
- a motivation letter ( including highlights of the previous research of the candidate and future career aspirations)
- documents proving the candidate has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic and/or PhD diploma from a foreign institution
A review of applications will start immediately after the deadline. Short-listed candidates will be invited for an interview within one month of the deadline.
Further information about: