Přehled

Who we are:

–          our Neurobiology group uses cellular models (human induced pluripotent stem cells) to study Alzheimer’s disease (AD) pathogenesis in vitro. Our in vitro models include a large portfolio of neuronal cell systems, including 2D neurons and 3D cerebral organoids. We aim to study, and ultimately to understand, the mechanisms of AD initiation and potential treatment for AD

–          we focus on mechanisms of neuronal differentiation, cellular senescence, metabolism, endosomal trafficking, and pathogen infections and how these processes influence the pathobiology of AD

–          our research is hypothesis-driven, and we seek to complement our analytical tools with high-throughput bulk-mRNA/miRNA seq analyses as well as single-cell seq transcriptomics to fully exploit the potential of our unique model systems.

–          as a part of the job, we offer participation in the relevant Bioinformatics training at EMBL-EBI or similar

–          we collaborate with numerous Czech and International Laboratories, including Max Planck Institute, Germany; Aarhus University, Denmark; Amsterdam UMC, The Netherlands, and others

–          our team currently consists of 7 Post-doctoral researchers, 1 Research Scientist, 2 Ph.D. students, and 1 undergrad student, who are all proficient in their fields of expertise


The successful candidate should:

–          be a researcher who has received a PhD or its equivalent within the last 7 years

–          be a researcher who has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic in the field of research with a working time of at least 0.5 full-time equivalent, or who has been PhD student (or equivalent) abroad

–          have a publishing record – in the last 3 years at least 3 publication outputs („articles“) above the field median (at least 2 of them in Q1) listed by the Web of Science


Specific criteria:

–          a scientific degree in computational biology or bioinformatics, or related fields

–          strong interest in single-cell omics. Experience in applied NGS data analysis such as transcriptomics (RNA-seq, scRNA-seq), additional experience with other omics methods is a plus

–          demonstrable experience in programming languages required for data analysis (R and/or Python)

–          proficiency with Linux/Unix; bash scripts

–          experience in building and maintaining bioinformatics tools/pipelines is a plus

–          ability to propose innovative solutions and critically evaluate data

–          excellent communication skills and teamwork

 

MU offers the opportunity to get:

–          highly competitive salary (dependent on the applicant’s skills and proficiency)

–          an exciting job in a dynamically-expanding university area

–          diverse and challenging work in an excellent research environment

–          initial appointment for 2 years

–          a professional team and pleasant working conditions

–          interaction with leading scientists in an inspiring, internationalized environment

–          a welcome service for the successful candidate and his/her family


Anticipated start date:
The position is available from July 2023 or upon agreement

The submission deadline is 28th February 2023

Please submit e-application at the website: https://www.muni.cz/o-univerzite/kariera-na-mu/volna-mista/75664.

The application should include:

–          a CV including a list of publication activity

–          a diploma (recognition for diplomas from foreign institutions)

–          two reference letters

–          documents proving the candidate has worked at least 2 whole years in the last 3 years outside the territory of the Czech Republic and/or PhD diploma from a foreign institution

A review of applications will start immediately after the deadline. Short-listed candidates will be invited for interview within one month of the deadline.

Further information about:

·         Medical Faculty is available at https://www.med.muni.cz/en

·         Masaryk University is available at https://www.muni.cz/en

·         Brno is available at https://www.gotobrno.cz/en/