Přehled

Charles University, Faculty of Pharmacy in Hradec Králové, represented by the Dean of the Faculty, announces an open competition according to the Act No. 111/1998 Coll., on Higher Education Institutions

for the project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM,
Project No.: CZ.02.01.01/00/22_008/0004607,

within the Operation Programme Johannes Amos Comenius (OP JAK), P 1: Research and Development, SO 1.1: Developing and enhancing research and innovation capacities and deploying advanced technologies,

to fill the research position:

FaF_VZ2_55: Researcher (junior), 0.8 FTE (80 %),

Place of work: Hradec Králové

Responsibilities:

  • Independent performance of the research activities in the relevant field.
  • Design, organisation of work, planning and execution of experiments for VZ2 (WP2).
  • Introduction and application of in vitro methods for testing pharmacokinetic drug interactions.
  • Work with in vitro cell cultures and recombinant enzymes.
  • Isolation and work with ex vivo primary cultures obtained from tumour biopsies.
  • Experiments associated with tumour microenvironment.
  • Drug combination studies.
  • Induction studies at gene and protein levels.
  • Gene/expression modifications (CRISPR-Cas9, siRNA, miRNA)
  • Preparation of recombinant proteins
  • Work with bioanalytical instruments (flow cytometer, qRT-PCR, ddPCR, Western blotting, confocal microscope, cell imaging system, sequencer).
  • Statistical data processing and publication of obtained results.
  • Presentation of the achieved results on an international level.
  • Involvement in the preparation of related national and international projects.
  • Participation in key project activities with an emphasis on application potential.

Profile:

  • A researcher who is no more than 7 years beyond the award of his/her academic Ph.D. or its equivalent (ISCED level 8 equivalent).
  • Completed university doctoral studies (Ph.D. degree) in a field of in the field with biomedical focus at a university in the Czech Republic or achieved a comparable degree at a foreign university no later than on the date of employment.
  • Junior researcher H-index ≥ 3 (is an advantage), min. 1 first-authored publication (preferably with IF ≥ 3), completed PhD studies, letter of recommendation from 2 experts in the field (at least 1 from a foreign institution), required education in the relevant field of research, grant activity is an advantage, active knowledge of English language.
  • Scientific and publication activity in the fields of pharmacology, biochemistry, molecular and cell biology.
  • Experience with pharmacological in vitro testing of small molecules in cell lines, experience with testing the anticancer activities of small molecules in cell lines, eventually in 3D-structured primary and/or in vivo models.
  • Previous experience and education in the fields of oncology, drug metabolism and gene regulation of biotransformation enzymes is an advantage.

Other knowledge and skills:

  • Prerequisites for excellent research work
  • Flexibility, diligence, thoroughness, and responsibility
  • Good organizational and communication skills
  • Ability to work both independently and in a team
  • High level of work commitment
  • Strong willingness to learn new things continuously

The application must include the following:

  • First and last name of the applicant
  • Date and place of birth
  • Nationality
  • Place of residence/current address
  • Date and signature
  • Contact information (email address, phone number)

Candidates are expected to submit the following annexes with an application:

  • CV including the list of publications, professional skills, and past research experience
  • Professional application letter
  • 2 letters of recommendation from recognized experts in their research field
  • Certified copy of a diploma (Ph.D. degree)
  • Other documents certifying required knowledge and expertise
  • Information duty and consent to the processing of personal data according to Regulation (EU) 2016/679 (General Data Protection Regulation) and Act No. 110/2019 Coll., on personal data processing, as amended

The application form and agreement, including an acknowledgment about providing personal data, are available for download below on this page http://www.faf.cuni.cz.

The estimated monthly wage: 62 000 CZK (1.0 FTE)

The start of work: 1 July, or can be negotiated

Type of employment contract: for 1-3 years, with the expectation that the contract will be extended until 29 February 2028.

Employment: part-time (0.8 FTE)

We offer:

  • Work for the prestigious educational and scientific institution of Charles University
  • Interesting work in cutting-edge research in the field of new technologies for translational research in pharmaceutical sciences
  • Opportunity to participate in cutting-edge research and be part of an international interdisciplinary team
  • Possibility of cooperation with foreign experts from all over the world
  • Specialized professional growth and continuous education in a field with the perspective of long-term employment
  • Foreign scientific internships and participation in international conferences

We also offer:

  • Part-time (0.8 FTE)
  • 5 weeks of vacation per year + 5 personal development days
  • Discounted calls for employees and their family members
  • Meal allowance and other contributions from the social fund (e.g., supplementary pension insurance or private life insurance, interest on a loan for housing needs)
  • possibility of using the services of the FAFÍK Children’s Group (a children’s group established at the Faculty of Pharmacy of the Charles University in Hradec Králové)
  • ČSOB incentive programme (a package of above-standard benefits for all employees)
  • UK benefits (discounts and benefits for UK employees at external entities)

We kindly ask you to send the application form with all required documents and attachments by post or email no later than 31. 5. 2024, 14:00, to the following address:

Charles University, Faculty of Pharmacy in Hradec Králové

Lenka Cermanová, DiS. – Personnel Department

Akademika Heyrovského 1203

500 03 Hradec Králové

Czech Republic

Email: hr@faf.cuni.cz

Please clearly mark the envelope „Job Announcement – NETPHARM Project – FaF_VZ2_55: Researcher (junior)“.

We kindly ask you to send your application with all the required documents and attachments because your application is incomplete without them, and you cannot be included in the list of candidates.

The announcer reserves the right to cancel the job announcement at any time during the course.

Contact person to provide further information on the content of the work:

prof. Ing. Vladimír Wsól, Ph.D. – Department of Biochemical Sciences

tel.: +420 495 067 370

e-mail: wsol@faf.cuni.cz

 

This project, No. CZ.02.01.01/00/22_008/0004607: New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, is co-financed by the European Union.