Přehled

We are seeking for a highly motivated scientist for EU-funded postdoctoral position in protein structural biology for experimental team at Loschmidt Laboratories, Masaryk University, Brno, Czech Republic (https://loschmidt.chemi.muni.cz/peg/).

JOB DESCRIPTION:

  • Perform protein expression, purification and biophysical characterization
  • Design and perform protein crystallization experiments
  • Collect X-ray diffraction data and determine protein-ligand complex structures
  • Adapt emerging structural techniques (nanocrystallography and cryo-EM)
  • Work in an inspiring and highly collaborative environment
  • Opportunities for further training, competitive salary and benefits package

PROFILE OF CANDIDATE:

  • Ph.D. in structural biology, molecular biology, biochemistry or biophysics
  • Experience with protein expression and purification
  • Previous experience with protein structural techniques (crystallography or cryo-EM)
  • Experience with biophysical and biochemical protein characterization
  • Willingness to learn new techniques (time-resolved crystallography or cryo-EM)
  • Ability to develop new concepts, goal-oriented and problem-solving skills
  • Good proficiency in English

APPLICATIONS:

  • Curriculum Vitae and motivation letter
  • Two letters of recommendation
  • Send your application to Jitka Sedlackova at jitkasedlackova@mail.muni.cz.

SELECTED PAPERS:

J. Am. Chem. Soc. 140: 17999, 2018 ACS Catalysis 8: 9420, 2018
J. Am. Chem. Soc. 137: 4988, 2015 ACS Catalysis 6: 7597, 2016
Chem. Rev. 113: 5871, 2013 Curr. Opin. Chem. Biol. 19: 8, 2014
Angewandte Chemie 52: 1959, 2013 Nature Chem. Biol. 10: 428, 2014